Actively exploitedKnown ransomware use

CVE-2021-38646 Microsoft Office Access Connectivity Engine Remote Code Execution Vulnerability

Microsoft Office Access Connectivity Engine contains an unspecified vulnerability which can allow for remote code execution.

From the CISA KEV catalogue version 2026.11.06, with Cybergen analysis. Updated 6 Nov 2026.

Our Assessment

Should You Worry?

Patch nowCybergen assessment
  • CISA confirmed exploitation in the wild and added it to the Known Exploited Vulnerabilities catalogue on 28 Mar 2022.
  • CISA lists it as known to be used in ransomware campaigns.
  • Rated High severity (CVSS 7.8, scored by Vendor).
  • It has been in the catalogue for 1,684 days. Systems still unpatched now have almost certainly been scanned for it.
The Vulnerability

What It Is

Microsoft Office Access Connectivity Engine Remote Code Execution Vulnerability

Affected Versions

ProductVersions
Microsoft Microsoft 365 Apps for Enterprise16.0.1 to before https://aka.ms/OfficeSecurityReleases
Microsoft Microsoft Office 2013 Service Pack 115.0.0 to before 5381.1000
Microsoft Microsoft Office 201616.0.0 to before 5215.1000
Microsoft Microsoft Office 201919.0.0 to before https://aka.ms/OfficeSecurityReleases

From the public CVE record, as supplied by the vendor. Always confirm against the vendor advisory.

From Watch to Action

What To Do Now

  1. 1

    Find it

    Search your asset inventory and external attack surface for Microsoft Office. Include cloud images, appliances and anything a supplier runs for you.

    Attack Surface Management
  2. 2

    Fix it

    Apply updates per vendor instructions.

    Vulnerability Management
  3. 3

    Hunt for compromise

    If an affected system was reachable before you patched, assume it may have been hit. Check logs, new accounts, web shells and outbound connections from the date of exposure.

    Incident Response
  4. 4

    Prove it is fixed

    Rescan or test the system after patching. Upgrades that fail silently and forgotten secondary instances are common.

    Penetration Testing

Not Sure If You Are Exposed?

Our attack surface and vulnerability teams can check your internet-facing estate for CVE-2021-38646 and every other exploited flaw on the list.

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